The statement highlights the notion that to succeed in a field that requires precision and strategy, like a killer's craft, one must possess analytical skills akin to those of a scientist. It implies that modern challenges necessitate a deeper understanding and methodical approach, rather than relying solely on brute force or instinct. This intellectual rigor is essential to navigate the complexities of any domain, including the darker aspects of human nature.

In Nabokov's "Lolita," this quote reflects the blending of intellect and moral ambiguity. It points to the idea that understanding, planning, and intellect are crucial in executing actions, even those that are ethically questionable. The interaction of science and morality invites readers to consider the implications of knowledge in shaping human behavior and the choices people make.