In Shakespeare's tragedy "Macbeth," the character Lady Macbeth experiences intense guilt and madness, which is epitomized in her famous line, "Out, damned spot! out, I say!" This occurs during a sleepwalking scene where she attempts to wash imaginary bloodstains from her hands, representing her deep remorse for her role in the murder of King Duncan. This moment illustrates the psychological consequences of ambition and moral corruption.
The quote signifies her inner turmoil and the inescapability of guilt. Despite her attempts to cleanse herself of her crimes, Lady Macbeth’s haunted mind reveals the profound impact of her actions. As she struggles with her conscience, it becomes clear that the quest for power can lead to devastating psychological effects, ultimately driving her to madness and despair.