In "Small Great Things," Jodi Picoult explores complex themes of racism, prejudice, and the capacity for both hate and love. The narrative shows how hatred can be ingrained in individuals from a young age, suggesting that such negative feelings are learned behaviors rather than innate qualities. This reflects Nelson Mandela’s assertion that hate is learned, indicating that if society can teach individuals to harbor hate, it also has the power to cultivate love and understanding.

The story revolves around the experiences of a Black nurse, Ruth, who faces discrimination and prejudice in her professional life. Through her journey, the novel highlights the challenges that arise from racial tension, demonstrating that love and empathy can overcome deeply rooted hate. Ultimately, the message reinforces that transformation is possible when individuals choose to embrace love instead of hate, promoting unity and compassion in a divided world.