In Sinclair Lewis's "Premium Collection Volume II," the importance of foundational knowledge in medicine is emphasized through the quote about a physician’s modest library, which consists of just three significant books: 'Gray's Anatomy', the Bible, and Shakespeare. This selection underscores the belief that understanding anatomy, morality, and the human experience through literature can equip one to become an exceptional doctor. The quote suggests that deep study and familiarity with these texts can greatly enrich a physician’s practice. 'Gray's Anatomy' provides essential medical knowledge, while the Bible and Shakespeare enhance ethical understanding and empathy—qualities crucial for a great medical professional. Through these literary references, Lewis advocates for a well-rounded education that merges science with the humanities.