In "Othello," Iago expresses a cynical view of reputation, claiming it is a superficial construct that often does not reflect true worth. He suggests that people can gain a good reputation without any real merit and can lose it without any deserving reason. This perspective highlights the fragility and often arbitrary nature of how society evaluates individuals.

Iago's statement serves as a commentary on human behavior and the importance placed on outward appearances. It reflects his manipulative nature, as he exploits the misconceptions tied to reputation to orchestrate his schemes. Ultimately, the quote encapsulates the play's exploration of identity, perception, and the consequences of valuing reputation over authenticity.