Sheepskin is noted for its durability, yet it requires careful handling due to the nature of ink application on its surface. Unlike paper, where ink penetrates the fibers, on sheepskin, ink merely rests atop, making it susceptible to being rubbed off. This quality necessitates a more delicate approach to using sheepskin as a writing medium.

In contrast, sixteenth-century paper was highly regarded for its quality, being crafted from rags and nearly acid-free. This composition allows it to endure over time remarkably well, showcasing the longevity and resilience of paper from that era. Thus, while sheepskin offers durability, it lacks the lasting imprint that high-quality paper provides.