The quote from William S. Burroughs' "Naked Lunch" highlights the severity of addiction and the concept of total need. It illustrates how a person suffering from addiction, like a drug addict, becomes consumed by their craving, losing all sense of morality and control. This state of total need can drive individuals to commit acts they would normally find reprehensible, showcasing the desperation that addiction brings.

Burroughs emphasizes that such individuals, akin to a rabid dog, are not in a position to make rational choices. Their actions, driven by an overwhelming compulsion, lead them to betray their values and relationships in a relentless pursuit of their addiction. The comparison underscores the idea that addiction transforms a person into a shadow of themselves, solely focused on satisfying their cravings, which can result in destructive behavior.