"Gone Crazy in Alabama" by Rita Williams-Garcia tells the story of three sisters, Delphine, Vonetta, and Fern, who travel to Alabama to visit their estranged grandmother. While there, they discover family secrets and learn more about their heritage. The narrative combines humor and poignant moments, highlighting the themes of family, identity, and resilience against challenges.

The characters, especially the sisters, navigate complex relationships and experience a range of emotions during their visit. The presence of the Soul Brothers and Sister Lou adds depth to their adventure, as they confront issues related to belonging and self-discovery, making the book a rich exploration of African American culture and familial bonds.