In John Dos Passos' "Manhattan Transfer," the author captures the unique essence and vibrancy of New York City. He reflects on the profound disappointment one feels when the city's allure fades, illustrating that its grandeur can leave a void in life when it loses its shine. New York stands as an unparalleled pinnacle in the world, making dissatisfaction in such a place all the more impactful.

The quote suggests that for many, New York represents the ultimate experience, but when that experience becomes mundane, it poses a serious challenge. The implied isolation becomes evident, as there seems to be no alternative that can rival its greatness. Dos Passos uses this sentiment to underline the city's significance in the lives of its inhabitants, emphasizing how it shapes their aspirations and realities.