Then are you working with the entire DNA strand? Grant asked. Oh no, Wu said. That's impossible. We've come a long way from the sixties, when it took a whole laboratory four years to decode a screen like this. Now the computers can do it in a couple of hours. But, even so, the DNA molecule is too big. We look only at the sections of the strand that differ from animal to animal, or from contemporary DNA. Only a few percent of the nucleotides differ from one species to the next. That's what we analyze, and it's still a big job.
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In the conversation between Grant and Wu, they discuss the challenges of DNA analysis and how technology has advanced since the 1960s. Wu explains that while it's no longer necessary to spend years decoding DNA, the sheer size of the DNA molecule makes it impractical to work with the entire strand. Instead, scientists focus on the specific sections that differ between species or contemporary DNA, as only a small percentage of nucleotides vary.

This process of analyzing these unique segments is still complex and time-consuming, emphasizing the intricacies involved in genetic research. The advancements in computer technology have significantly sped up the analysis, reducing what once took years to mere hours. Despite these improvements, the task remains substantial, highlighting the continued effort required in the field of genetics.

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January 28, 2025

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