In Jodi Picoult's book "Handle with Care," the author explores the complex emotions faced by mothers who have experienced the loss or suffering of their children. The quote emphasizes the deep bond among mothers who navigate the pain of having children with serious ailments or those they have lost, revealing a shared sense of guilt and unresolved questions about their choices. These mothers grapple with their experiences, often haunted by what could have been.

Picoult captures the profound sadness and reflection that comes with motherhood in the face of tragedy. Whether it's mourning the life of a child who was never fully realized or caring for a child with challenges, each mother's journey is unique yet interconnected, highlighting the universal themes of love, loss, and the struggle to find meaning in difficult circumstances.