In George Eliot's novel "Middlemarch," the theme of unfulfilled aspirations and the pain of striving for greatness is poignantly expressed. The quote reflects a deep sorrow felt by individuals who admire excellence, yet find themselves unable to attain it despite their best efforts. This sentiment resonates with anyone who has experienced the anguish of working towards a lofty goal, only to face disappointment. It highlights the struggles between ambition and reality in the lives of the characters within the story.

This exploration of yearning and failure is central to "Middlemarch," illustrating how love for something superior can amplify sorrow when one falls short. Eliot masterfully captures the essence of human longing and the complexity of dreams. The characters' journeys reflect the universal experience of reaching for greatness, ultimately leading to profound introspection and understanding of one's limitations and desires.