The quote "And so, my hopes come back in smoke" from Miguel de Cervantes Saavedra's "Don Quixote" reflects the theme of disillusionment that runs throughout the novel. The protagonist, Don Quixote, embarks on grand adventures fueled by his ideals and imagination, only to face the harsh realities that often extinguish his dreams. This moment captures the bittersweet essence of aspiration versus reality, illustrating how hopes can dissipate like smoke, leaving behind a sense of loss.