In her book "Handle with Care," Jodi Picoult explores the complexities of emotions and relationships, delving into the profound idea that one can feel a deep sense of longing for someone they've never truly met. This invites readers to reflect on the connections we form with others, even if those individuals are not part of our direct experiences. Such feelings can stem from shared histories or an innate sense of empathy.

The quote "You can miss a person you've never known" encapsulates the bittersweet nature of human emotions. It suggests that the longing for someone, whether based on ideals, fantasies, or familial ties, speaks to our capacity for love and connection, highlighting the significance of the uncharted paths in our emotional landscapes.