In John Irving's novel, "The Fourth Hand," a character grapples with feelings of inadequacy and failure, particularly in relation to his sexuality and personal identity. The mention of "feeling like a failed sexual predator" highlights his internal conflict and the weight of societal expectations regarding masculinity and sexual power. This moment of vulnerability is intensified by the situation involving a pregnant character named Mary, which serves as a catalyst for his shame and self-reflection.

The dynamics of relationships and the consequences of desire are central themes in the story. The character's struggle reflects broader issues of intimacy, responsibility, and the often complicated nature of human connections. Through these challenges, Irving explores the complexities of love, desire, and the impact of life's unexpected turns, all of which contribute to the protagonist's journey towards understanding himself and his place in the world.