In Edgar Allan Poe's work, the narrator observes Hop-Frog's aversion to wine, acknowledging that it affects the disabled jester in a deeply unsettling manner. The drink tends to exhilarate Hop-Frog, pushing him towards a state of mania that leaves him feeling uncomfortable and distressed. This insight into Hop-Frog's character suggests that he is already burdened by his condition, and the addition of alcohol only exacerbates his suffering.

This reflection highlights the vulnerability of individuals like Hop-Frog, whose mental state can be significantly impacted by external factors. It raises questions about the broader implications of social interactions and the pressures faced by those who are marginalized. Poe's exploration of these themes underscores a deep empathy for characters grappling with their limitations and the complexities of their emotions.