He told me that a German doctor named Wolff figured it out in the 1800s by studying X-rays of infants' hips as they transitioned from crawling to walking. "A whole new evolution of bone structure takes place to support the mechanical loads associated with walking," said Lang. "Wolff had the great insight that form follows function." Alas, Wolff did not have the great insight that cancer follows gratuitous X-raying with primitive nineteenth-century X-ray machines.

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In the 1800s, a German doctor named Wolff made significant discoveries regarding human bone structure. By examining X-rays of infants as they progressed from crawling to walking, he understood that bones undergo evolution to accommodate the demands of weight-bearing activities. This led to the principle that the shape of bones is influenced by their function, summarized in Wolff's insight that "form follows function," as explained by Lang in Mary Roach's book, "Packing for Mars."

However, while Wolff's work was groundbreaking, he did not foresee the potential negative effects of excessive X-ray exposure. The primitive technology of the time posed risks, particularly related to cancer, which contrasts sharply with the advancements we have today in medical imaging. Roach's exploration reveals how our understanding of science and medical practices continues to evolve, often learning from past missteps.

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March 31, 2025

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