The quote "I get the willies when I see closed doors" from Joseph Heller's book, Something Happened, expresses a deep sense of anxiety and apprehension. This reaction to closed doors suggests that they symbolize uncertainty and the unknown, evoking feelings of discomfort in the character. It highlights how closed doors can represent isolation and the fear of what lies beyond them. This sensation can resonate with anyone who has faced situations where the outcome is uncertain and hidden from view.