In Vladimir Nabokov's novel "Despair," the protagonist expresses a profound feeling of isolation and loneliness that has persisted throughout his life. This sentiment of loneliness serves as a central theme in the book, highlighting the character's struggle with his inner turmoil and the sense of disconnection from the world around him.

The quote, "I was always lonely and I am lonely still," encapsulates this ongoing battle with despair. It reflects not only a personal experience but also a universal condition, suggesting that loneliness is an intrinsic part of human existence that can persist despite external circumstances. Nabokov's exploration of this theme invites readers to contemplate the nature of despair and the complexities of loneliness.