In "Oryx and Crake," the protagonist Snowman reflects on a world filled with the remnants of cultural and historical significance. As he navigates through a lush yet decaying environment, he conjures memories of great works of art and literature, from Homer's epics to Shakespeare's plays and the music of renowned composers. This evokes a sense of loss, as these achievements symbolize humanity's potential which now seems overshadowed by destruction and ruin.

The mention of significant figures and milestones like the polio vaccine, heart transplants, and various masterpieces underscores the contrast between human creativity and the current desolation. Snowman's journey serves as a poignant reminder of both the marvels of human innovation and the fragility of civilization, illustrating the consequences of a world where such brilliance is at risk of being forgotten.