In Jodi Picoult's book "The Tenth Circle," the quote reflects the idea that personal experiences can deepen our appreciation for what we have. It suggests that sometimes, we only recognize the true worth of something once we face the potential loss of it. This theme highlights how challenges can lead to greater awareness and gratitude in life.

The narrative encourages readers to consider their own relationships and the significance of the people and things around them. By experiencing near loss, individuals often gain a stronger perspective on what truly matters, reinforcing the notion that value is often taken for granted until it's challenged.