In Nick Hornby's book "A Long Way Down," the author explores the theme of unhappiness and its pervasive effects on daily life. The quote suggests that when a person is feeling unhappy, even the simplest pleasures like reading, eating, or sleeping become tainted by their emotional state. This disconnection leads to an internal closure that further exacerbates feelings of distress.

The character's reflections highlight a profound truth about how emotional well-being influences our ability to enjoy life. When struck by unhappiness, individuals may find themselves trapped in a cycle of negativity, where their enjoyment of the world is diminished, deepening their sense of isolation and sorrow.