The quote reflects the painful irony of unrequited love, where one person longs for someone who has moved on, while the other person is infatuated with someone who is indifferent to their feelings. It highlights the emotional turmoil that can arise from unbalanced affections, emphasizing the sadness and frustration inherent in such situations.
The speaker expresses a sense of sorrow that love often brings about contradictions, where the heart's desires do not align with reality. This juxtaposition of feelings leads to a deep sense of loss and lamentation, showcasing Shakespeare's understanding of the complexities of love and its ability to induce both joy and heartache.