The quote from Shakespeare's "Richard III" reflects the profound influence of sin, death, and hell on the character of Richard III. It suggests that Richard is marked by his malevolent actions and the moral decay that accompanies them. The presence of these dark forces implies that he is inextricably linked to evil, as if he carries the burden of his misdeeds, which also impacts those around him.

Furthermore, the mention of "all their ministers attend on him" indicates that the consequences of his sins are not solitary; rather, they follow him relentlessly. This highlights the idea that Richard's pursuit of power and his ruthless nature have drawn the attention of the very forces of darkness, suggesting that he is under constant surveillance by the repercussions of his actions. Ultimately, the quote encapsulates the themes of ambition and moral corruption central to the play.