In "Extremely Loud and Incredibly Close," Jonathan Safran Foer reflects on the transient nature of relationships. Many individuals come into our lives, sometimes leaving a significant impact, while others may drift away without notice. This highlights the importance of being open to new connections, as every encounter serves a unique purpose in our life's journey.

However, this openness comes with a necessity to accept the departure of others. Holding on too tightly can hinder personal growth and the ability to embrace new experiences. Foer's insight encourages a balance between welcoming new people and gracefully letting go of those who move on, ensuring that we remain receptive to life’s ongoing changes.