In John Sandford's book "Invisible Prey," the author addresses the impact of excessive Botox use on a person's ability to express genuine emotions. When individuals undergo too many treatments, they may lose the ability to display authentic reactions, leading them to artificially simulate emotions. This creates a confusing situation where it becomes challenging to differentiate between natural and forced responses.

The quote highlights the ironic predicament faced by those who rely heavily on Botox for aesthetic improvement. Instead of enhancing their expressions, overuse can result in a struggle to appear authentic, ultimately detracting from their humanity and complicating everyday interactions.