"Things shouldn't depend on such minor details," suggests that small actions or events can have significant consequences. A sneeze can cause serious accidents, and removing a tiny stone can trigger a devastating avalanche, highlighting how minor factors can lead to major outcomes.
The quote also reflects on the idea that living without fully understanding how things happen might be a source of comfort. If one can die without knowing the full reasons behind events, it implies that sometimes ignorance or acceptance can make life easier, offering a sense of relief from the need to find every explanation.