You got some idealist idea about man being some noble creature … and all this crap about how we can change human nature. You can't change it, you're beating your head against a brick wall. People have had a couple of million years to change and they ain't changed yet, have they?
This quote emphasizes the futility of trying to alter the inherent characteristics of humanity, pointing out a long-standing acceptance of human flaws as unchangeable over millennia.