This quote from Philip Pullman's "The Amber Spyglass" reflects on the tragic experiences of individuals who, feeling overwhelmed by suffering and despair, sought death as a means of escape. It highlights the profound pain these "poor souls" endured, leading them to believe that death would bring them the relief they could not find in life. Their longing for peace is deeply tragic, suggesting that life can bring unbearable burdens.

However, the quote also emphasizes the harsh reality that death does not solve their problems. Instead of achieving the promised rest, they find that their conditions may worsen, and they experience a permanent state devoid of life. Pullman poignantly underlines the irreversible nature of life and death, reminding readers that there is no way to return once a choice has been made, further deepening the sense of despair faced by those who contemplate such drastic measures.