Timothy Leary famously compared personal computers to LSD, emphasizing their ability to expand consciousness and facilitate new experiences. He viewed the emerging technology as a transformative tool that could alter perceptions and enhance creativity, similar to the psychedelic effects of drugs.

Later, Leary adapted his mantra to "Turn on, boot up, jack in," reflecting the evolving relationship between humans and technology. This phrase encapsulates the idea of engaging deeply with computers, suggesting that the act of using technology can lead to profound personal insights and connections, much like the experiences sought through psychedelics.