The quote by Lama Surya Das from "The Big Questions: A Buddhist Response to Life's Most Challenging Mysteries" illustrates the human condition of seeking meaning even in the absence of certainty. It emphasizes the inherent obligation we have to act as if life possesses significance, highlighting the existential struggle many face when grappling with uncertainty about existence.

This perspective encourages us to create our own meaning and purpose in life, regardless of the ambiguities and challenges we encounter. By living as if life holds value, we can derive a sense of fulfillment and connection, enriching our experiences despite the lack of definitive answers to life's profound questions.